Champions Oncology

Syngeneic Models

Champions is constantly updating the data in our bank and as such, please reach out to your local BD contact to provide you with the most up-to-date information possible. We can readily provide customized, comprehensive, and easy to navigate spreadsheets to meet your needs so please do not hesitate to reach out to us at database@championsoncology.com.

Download charts for all syngeneic cell lines (5.5MB zip file).


Click any row for additional details.
 
Cell Line Tumor Type Immunogenic? Pilot data Treatments screened Characterization (completed/proposed)
4T-1 Breast No; refractory Yes α-PD-1/α-CTLA-4/α-OX40 Drug screen; T/B cells; MDSCs; macrophages
MC38 Colon Yes Yes α-PD-1/α-CTLA-4/α-OX40 Drug screen; T/B cells; MDSCs; macrophages; NK cells
LLC Lung No; refractory Yes α-PD-1/α-CTLA-4/α-OX40 Drug screen
CT26 Colon Yes Yes α-PD-1/α-CTLA-4/α-OX40 Drug screen
B16F10 Melanoma Partially Yes α-PD-1/α-CTLA-4/α-OX40 Drug screen
EMT6 Breast TBD Yes α-PD-1/α-CTLA-4 Drug screen
RENCA Kidney TBD Yes α-PD-1/α-CTLA-4 Drug screen