Champions is constantly updating the data in our bank and as such, please reach out to your local BD contact to provide you with the most up-to-date information possible. We can readily provide customized, comprehensive, and easy to navigate spreadsheets to meet your needs so please do not hesitate to reach out to us at database@championsoncology.com.
Download charts for all syngeneic cell lines (5.5MB zip file).
Cell Line | Tumor Type | Immunogenic? | Pilot data | Treatments screened | Characterization (completed/proposed) | |
---|---|---|---|---|---|---|
4T-1 | Breast | No; refractory | Yes | α-PD-1/α-CTLA-4/α-OX40 | Drug screen; T/B cells; MDSCs; macrophages | |
MC38 | Colon | Yes | Yes | α-PD-1/α-CTLA-4/α-OX40 | Drug screen; T/B cells; MDSCs; macrophages; NK cells | |
LLC | Lung | No; refractory | Yes | α-PD-1/α-CTLA-4/α-OX40 | Drug screen | |
CT26 | Colon | Yes | Yes | α-PD-1/α-CTLA-4/α-OX40 | Drug screen | |
B16F10 | Melanoma | Partially | Yes | α-PD-1/α-CTLA-4/α-OX40 | Drug screen | |
EMT6 | Breast | TBD | Yes | α-PD-1/α-CTLA-4 | Drug screen | |
RENCA | Kidney | TBD | Yes | α-PD-1/α-CTLA-4 | Drug screen |