Champions Oncology

Syngeneic Models

Champions is constantly updating the data in our bank and as such, please reach out to your local BD contact to provide you with the most up-to-date information possible. We can readily provide customized, comprehensive, and easy to navigate spreadsheets to meet your needs so please do not hesitate to reach out to us at database@championsoncology.com.


Click any row for additional details.
 
Cell Line Tumor Type Immunogenic Pilot data Treatments screened Characterization (completed/proposed)
4T-1Breast No; refractoryYes a-PD-1/a-CTLA-4/a-OX40Growth; T/B cells; MDSCs; macrophages
MC38ColonYesYes a-PD-1/a-CTLA-4/a-OX40Growth; T/B cells; MDSCs; macrophages; NK cells
LLCLungNo; refractoryYes a-PD-1/a-CTLA-4/a-OX40Growth
CT26ColonYesYes a-PD-1/a-CTLA-4/a-OX40Growth
B16F10MelanomaPartiallyYes a-PD-1/a-CTLA-4/a-OX40Growth
RENCAKidneyTBDNo a-PD-1/a-CTLA-4/a-OX40Proposed: growth; T/B cells; MDSCs; macrophages, NK cells